ITM 6.x is a pretty simple system and day-to-day, I don't feel that it needs too much hand holding.
Of course, we never leave the poor thing alone and we're constantly upgrading the system, adding agents and changing situations :)
So, every now and then a problem appears.
There is an excellent presentation which summarizes basic troubleshooting and where to look for problems.
(Logs, trace levels, debugging, process flow and much much more)
ITM 6.1 Problem Determination Tools and Best Practices
It also has links to a series of scripts in OPAL which will enable you to see what's going on in your ITM environment in a simpler way.
Simpler for tech people of course, don't let managers see these scripts :)
for the scripts, go to the OPAL catalog
Enjoy :)